Blood Pressure Changes Following Antihypertensive Medication Reduction, by Drug Class and Dose Chosen for Withdrawal: Exploratory Analysis of Data From the OPTiMISE Trial

• Main Authors: James P. Sheppard (Author), Mark Lown (Author), Jenni Burt (Author), Gary A. Ford (Author), F. D. Richard Hobbs (Author), Paul Little (Author), Jonathan Mant (Author), Rupert A. Payne (Author), Richard J. McManus (Author), On behalf of the OPTiMISE Investigators (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: Deprescribing of antihypertensive drugs is recommended for some older patients with polypharmacy, but there is little evidence to inform which drug (or dose) should be withdrawn. This study used data from the OPTiMISE trial to examine whether short-term outcomes of deprescribing vary by drug c...