Initial dosage optimisation of cyclosporine in Chinese paediatric patients undergoing allogeneic haematopoietic stem cell transplantation based on population pharmacokinetics: a retrospective study

• Main Authors: Yan Li (Author), Sha Liu (Author), Hua Jiang (Author), Wei Zheng (Author), Min Huang (Author), Huanwen Feng (Author), Xianggui Wang (Author), Yuxian Lin (Author), Haojie Qiu (Author), Teng Fong Chan (Author), Xiaolan Mo (Author), Jiali Li (Author)
• Format: Book
• Published: BMJ Publishing Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective Improved understanding of cyclosporine A (CsA) pharmacokinetics in children undergoing allogeneic haematopoietic stem cell transplantation (allo-HSCT) is crucial for effective prevention of acute graft-versus-host disease and medication safety. The aim of this study was to establish a popu...