Quantitative polymerase chain reaction in paucibacillary leprosy diagnosis: A follow-up study.

• Main Authors: Raquel R Barbieri (Author), Fernanda S N Manta (Author), Suelen J M Moreira (Author), Anna M Sales (Author), José A C Nery (Author), Lilian P R Nascimento (Author), Mariana A Hacker (Author), Antônio G Pacheco (Author), Alice M Machado (Author), Euzenir M Sarno (Author), Milton O Moraes (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

OBJECTIVE:The diagnosis of paucibacillary (PB) leprosy cases remains a challenge because of the absence of a confirmatory laboratory method. While quantitative polymerase chain reaction (qPCR) has been shown to provide reliable sensitivity and specificity in PB diagnoses, a thorough investigation of...