Case report: Supratherapeutic tacrolimus concentrations with nirmatrelvir/ritonavir in a lung transplant patient: a case report using Rifampin for reversal

• Hoofdauteurs: Yu Xiong (Auteur), Xiaoxing Wang (Auteur), Shu Li (Auteur), Qian Zhang (Auteur), Lijuan Guo (Auteur), Wenhui Chen (Auteur), Zhixia Zhao (Auteur), Lihong Liu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Paxlovid (nirmatrelvir/ritonavir) is an antiviral drug used to treat COVID-19, nirmatrelvir, a SARS-CoV-2 main protease inhibitor, works by inhibiting viral replication in the early stages, and ritonavir is a strong cytochrome P450 (CYP) 3A inhibitor that helps the nirmatrelvir reach and maintain th...