Loxapine for Treatment of Patients With Refractory, Chemotherapy-Induced Neuropathic Pain: A Prematurely Terminated Pilot Study Showing Efficacy But Limited Tolerability

• Main Authors: Sven Schmiedl (Author), David Peters (Author), Oliver Schmalz (Author), Anke Mielke (Author), Tanja Rossmanith (Author), Shirin Diop (Author), Martina Piefke (Author), Petra Thürmann (Author), Achim Schmidtko (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuropathic pain is a debilitating and commonly treatment-refractory condition requiring novel therapeutic options. Accumulating preclinical studies indicate that the potassium channel Slack (KNa1.1) contributes to the processing of neuropathic pain, and that Slack activators, when injected into mic...