Hepatic Differentiation of Murine Disease-Specific Induced Pluripotent Stem Cells Allows Disease Modelling In Vitro

Direct reprogramming of somatic cells into pluripotent cells by retrovirus-mediated expression of OCT4, SOX2, KLF4, and C-MYC is a promising approach to derive disease-specific induced pluripotent stem cells (iPSCs). In this study, we focused on three murine models for metabolic liver disorders: the...

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Main Authors: Reto Eggenschwiler (Author), Komal Loya (Author), Malte Sgodda (Author), Francoise André (Author), Tobias Cantz (Author)
Format: Book
Published: Hindawi Limited, 2011-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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