Case Report: A Novel Heterozygous Mutation of CD2AP in a Chinese Family With Proteinuria Leads to Focal Segmental Glomerulosclerosis

• Main Authors: Yu-Xing Liu (Author), Ai-Qian Zhang (Author), Fang-Mei Luo (Author), Yue Sheng (Author), Chen-Yu Wang (Author), Yi Dong (Author), Liangliang Fan (Author), Lv Liu (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Fag: article
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Idiopathic focal segmental glomerulosclerosis (FSGS) is a relatively frequent kidney disorder that manifest clinically as proteinuria and progressive loss of renal function. Genetic factors play a dominant role in the occurrence of FSGS. CD2-associated protein (CD2AP) is an adapter molecule and is e...