Cellular mechanisms underlying Pax3-related neural tube defects and their prevention by folic acid

• Main Authors: Sonia Sudiwala (Author), Alexandra Palmer (Author), Valentina Massa (Author), Alan J. Burns (Author), Louisa P. E. Dunlevy (Author), Sandra C. P. de Castro (Author), Dawn Savery (Author), Kit-Yi Leung (Author), Andrew J. Copp (Author), Nicholas D. E. Greene (Author)
• Format: Book
• Published: The Company of Biologists, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neural tube defects (NTDs), including spina bifida and anencephaly, are among the most common birth defects worldwide, but their underlying genetic and cellular causes are not well understood. Some NTDs are preventable by supplemental folic acid. However, despite widespread use of folic acid supplem...