Profile of the tprK gene in primary syphilis patients based on next-generation sequencing.

• Main Authors: Dan Liu (Author), Man-Li Tong (Author), Xi Luo (Author), Li-Li Liu (Author), Li-Rong Lin (Author), Hui-Lin Zhang (Author), Yong Lin (Author), Jian-Jun Niu (Author), Tian-Ci Yang (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The highly variable tprK gene of Treponema pallidum has been acknowledged to be one of the mechanisms that causes persistent infection. Previous studies have mainly focused on the heterogeneity in tprK in propagated strains using a clone-based Sanger approach. Few studies have investigate...