Effect of binders on 500mg metformin hydrochloride tablets produced by wet granulation

Effect of binders on 500mg metformin hydrochloride tablets produced by wet granulation

Metformin hydrochloride (MH) is an oral hypoglycemic agent and a high-dose drug that has poor flow and compression properties. In this study, the feasibility of developing adequate, low cost 500mg tablets of metformin hydrochloride by wet granulation was tested with several binders (Starch / PVP K30...

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Main Authors: L.C. Block (Author), L.O. Schmeling (Author), A.G. Couto (Author), M.A.S. Silva (Author), M.P. Tagliari (Author), T.M.B. Bresolin (Author), S.C. Mourão (Author)
Format: Book
Published: São Paulo State University (UNESP), 2009-05-01T00:00:00Z.
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3rd Floor Main Library

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