Effects of Mitragynine and a Crude Alkaloid Extract Derived from Mitragyna speciosa Korth. on Permethrin Elimination in Rats

• Main Authors: Kachamas Srichana (Author), Benjamas Janchawee (Author), Sathaporn Prutipanlai (Author), Pritsana Raungrut (Author), Niwat Keawpradub (Author)
• Format: Book
• Published: MDPI AG, 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Detoxification and elimination of permethrin (PM) are mediated by hydrolysis via carboxylesterase (CES). Mitragyna speciosa (kratom) contains mitragynine (MG) and other bioactive alkaloids. Since PM and MG have the same catalytic site and M. speciosa is usually abused by adding other ingredients suc...