Proinflammatory and Anti-Inflammatory Cytokines Mediated by NF-κB Factor as Prognostic Markers in Mammary Tumors

• Main Authors: Gustavo Rodrigues Martins (Author), Gabriela Bottaro Gelaleti (Author), Marina Gobbe Moschetta (Author), Larissa Bazela Maschio-Signorini (Author), Debora Ap. Pires de Campos Zuccari (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammation results in the production of cytokines, such as interleukin- (IL-) 4 and IL-10 with immunosuppressive properties or IL-6 and TNF-α with procarcinogenic activity. Furthermore, NF-κB is the major link between inflammation and tumorigenesis. This study verified the interaction between acti...