Nucleus accumbens inflammation mediates anxiodepressive behavior and compulsive sucrose seeking elicited by saturated dietary fat

• Main Authors: Léa Décarie-Spain (Author), Sandeep Sharma (Author), Cécile Hryhorczuk (Author), Victor Issa-Garcia (Author), Philip A. Barker (Author), Nathalie Arbour (Author), Thierry Alquier (Author), Stephanie Fulton (Author)
• Format: Book
• Published: Elsevier, 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The incidence of depression is significantly compounded by obesity. Obesity arising from excessive intake of high-fat food provokes anxiodepressive behavior and elicits molecular adaptations in the nucleus accumbens (NAc), a region well-implicated in the hedonic deficits associated with d...