Case report of a 3-year-old girl with pleuropulmonary blastoma and family history of a tumor predisposition syndrome with c. 2830 gene mutation in DICER1

• Main Authors: Y. Puckett (Author), J. Howe (Author), D. Vane (Author), A. Agarwal (Author), J.R. Batanian (Author), J. Greenspon (Author)
• Format: Book
• Published: Elsevier, 2015-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pleuropulmonary blastoma (PPB) is a childhood mesenchymal pleural-based tumor that is associated with a germline mutation in DICER1 gene in familial PPB. It occurs most commonly in children between the ages of 2 and 5. Approximately 25% of patients have familial cancer syndrome which can include dif...