On a model-based approach to improve intranasal spray targeting for respiratory viral infections

• Main Authors: Mohammad Mehedi Hasan Akash (Author), Yueying Lao (Author), Pallavi A. Balivada (Author), Phoebe Ato (Author), Nogaye K. Ka (Author), Austin Mituniewicz (Author), Zachary Silfen (Author), Julie D. Suman (Author), Arijit Chakravarty (Author), Diane Joseph-McCarthy (Author), Saikat Basu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The nasopharynx, at the back of the nose, constitutes the dominant initial viral infection trigger zone along the upper respiratory tract. However, as per the standard recommended usage protocol ("Current Use", or CU) for intranasal sprays, the nozzle should enter the nose almost verticall...