Therapeutic potential of tucidinostat, a subtype-selective HDAC inhibitor, in cancer treatment

• Main Authors: Yichen Sun (Author), Jing Han Hong (Author), Zhiqiang Ning (Author), Desi Pan (Author), Xin Fu (Author), Xianping Lu (Author), Jing Tan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Histone deacetylase (HDAC) is one of the most characterized epigenetic modifiers, modulating chromatin structure and gene expression, which plays an important role in cell cycle, differentiation and apoptosis. Dysregulation of HDAC promotes cancer progression, thus inhibitors targeting HDACs have ev...