Therapeutic potential of tucidinostat, a subtype-selective HDAC inhibitor, in cancer treatment

• मुख्य लेखकों: Yichen Sun (लेखक), Jing Han Hong (लेखक), Zhiqiang Ning (लेखक), Desi Pan (लेखक), Xin Fu (लेखक), Xianping Lu (लेखक), Jing Tan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Histone deacetylase (HDAC) is one of the most characterized epigenetic modifiers, modulating chromatin structure and gene expression, which plays an important role in cell cycle, differentiation and apoptosis. Dysregulation of HDAC promotes cancer progression, thus inhibitors targeting HDACs have ev...