Azathioprine and 6-mercaptopurine-induced intrahepatic cholestasis of pregnancy: Case report and review of the literature

• Main Authors: Maya Frank Wolf (Author), Ronen Sloma (Author), Luiza Akria (Author), Eli Rimon (Author), Yifat Wiener (Author), Michal Carmiel Haggai (Author), Lior Lowenstein (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Azathioprine, a prodrug of 6-mercaptopurine (6-MP), is used in the treatment of inflammatory bowel disease and may be continued during pregnancy. Acute cholestatic liver injury has been reported to occur with azathioprine. We aimed to examine azathioprine related cholestasis effect on pre...