Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA mutations, and loss of oxidative phosphorylation complex I integrity with oncocytic tumors

• প্রধান লেখক: Oleksiy Tsybrovskyy (Author), Monica De Luise (Author), Dario deBiase (Author), Leonardo Caporali (Author), Claudio Fiorini (Author), Giuseppe Gasparre (Author), Valerio Carelli (Author), Dominik Hackl (Author), Larisa Imamovic (Author), Silke Haim (Author), Manuel Sobrinho‐Simões (Author), Giovanni Tallini (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2022-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Papillary thyroid carcinoma tall cell variant (PTC‐TCV), a form of PTC regarded as an aggressive subtype, shares several morphologic features with oncocytic tumors. Pathogenic homoplasmic/highly heteroplasmic somatic mitochondrial DNA (mtDNA) mutations, usually affecting oxidative phosphory...