In vitro schistosomicidal activity of the lignan (−)-6,6'-dinitrohinokinin (DNHK) loaded into poly(lactic-co-glycolic acid) nanoparticles against Schistosoma mansoni

• Main Authors: Thaís C. Lima (Author), Rodrigo Lucarini (Author), Priscilla P. Luz (Author), Emerson H. de Faria (Author), Liziane Marçal (Author), Lizandra G. Magalhães (Author), Fernanda R. Badoco (Author), Viviane R. Esperandim (Author), Eduardo F. Molina (Author), Rosangela S. Laurentz (Author), Regiane G. Lima (Author), Wilson R. Cunha (Author), Jairo K. Bastos (Author), Marcio L. Andrade Silva (Author)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Context: (−)-6,6'-Dinitrohinokinin (DNHK) display remarkable antiparasitic activity and was, therefore, incorporated into a nanoparticle formulation. Objective: Incorporation of DNHK in poly lactic-co-glycolic acid (PLGA) nanoparticles aiming to improve its biological activities. Materials and...