In vitro schistosomicidal activity of the lignan (−)-6,6'-dinitrohinokinin (DNHK) loaded into poly(lactic-co-glycolic acid) nanoparticles against Schistosoma mansoni

• Main Authors: Thaís C. Lima (Author), Rodrigo Lucarini (Author), Priscilla P. Luz (Author), Emerson H. de Faria (Author), Liziane Marçal (Author), Lizandra G. Magalhães (Author), Fernanda R. Badoco (Author), Viviane R. Esperandim (Author), Eduardo F. Molina (Author), Rosangela S. Laurentz (Author), Regiane G. Lima (Author), Wilson R. Cunha (Author), Jairo K. Bastos (Author), Marcio L. Andrade Silva (Author)
• פורמט: ספר
• יצא לאור: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Context: (−)-6,6'-Dinitrohinokinin (DNHK) display remarkable antiparasitic activity and was, therefore, incorporated into a nanoparticle formulation. Objective: Incorporation of DNHK in poly lactic-co-glycolic acid (PLGA) nanoparticles aiming to improve its biological activities. Materials and...