Cigarette Smoke Extract Stimulates MMP-2 Production in Nasal Fibroblasts via ROS/PI3K, Akt, and NF-κB Signaling Pathways

• Main Authors: Joo-Hoo Park (Author), Jae-Min Shin (Author), Hyun-Woo Yang (Author), Tae Hoon Kim (Author), Seung Hoon Lee (Author), Heung-Man Lee (Author), Jae-Gu Cho (Author), Il-Ho Park (Author)
• Format: Book
• Published: MDPI AG, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cigarette smoke exposure has been shown to be associated with chronic rhinosinusitis and tissue remodeling. The present study aimed to investigate the effects of cigarette smoke extract (CSE) on matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) production in nasal fibro...