15-Lipoxygenase-1 Is Involved in the Effects of Atorvastatin on Endothelial Dysfunction

• Main Authors: Peng Zhang (Author), Xin Xing (Author), Chunxiao Hu (Author), Hui Yu (Author), Qian Dong (Author), Guanglei Chang (Author), Shu Qin (Author), Jian Liu (Author), Dongying Zhang (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Statins exert pleiotropic effects on endothelial cells in addition to lowering cholesterol. 15-Lipoxygenase-1 (ALOX15) has been implicated in vascular inflammation and disease. The relationship between atorvastatin and ALOX15 was investigated using a rat carotid artery balloon-injury model. Hematoxy...