An immunocompetent patient with a nonsense mutation in NHEJ1 gene

• Main Authors: Hossein Esmaeilzadeh (Author), Mohammad Reza Bordbar (Author), Zahra Hojaji (Author), Parham Habibzadeh (Author), Dorna Afshinfar (Author), Mohammad Miryounesi (Author), Majid Fardaei (Author), Mohammad Ali Faghihi (Author)
• Format: Book
• Published: BMC, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background DNA double-strand breaks (DSBs) are among the most deleterious types of DNA damage. DSBs are repaired by homologous recombination or non-homologous end-joining (NHEJ). NHEJ, which is central to the process of V(D)J recombination is the principle pathway for DSB repair in higher e...