Inhibition of Human Efflux Transporter ABCC2 (MRP2) by Self-emulsifying Drug Delivery System: Influences of Concentration and Combination of Excipients

• मुख्य लेखकों: Liang Li (लेखक), Tao Yi (लेखक), Christopher Wai-kei Lam (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2014-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

PURPOSE: This study investigated influences of concentration and combination of excipients, commonly used in self-emulsifying drug delivery systems (SEDDS), on inhibition of human efflux transporter ABCC2 (MRP2). METHODS: Ten commonly used excipients of SEDDS with inhibitory effect on MRP2 including...