Inhibition of Human Efflux Transporter ABCC2 (MRP2) by Self-emulsifying Drug Delivery System: Influences of Concentration and Combination of Excipients

• Päätekijät: Liang Li (Tekijä), Tao Yi (Tekijä), Christopher Wai-kei Lam (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2014-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

PURPOSE: This study investigated influences of concentration and combination of excipients, commonly used in self-emulsifying drug delivery systems (SEDDS), on inhibition of human efflux transporter ABCC2 (MRP2). METHODS: Ten commonly used excipients of SEDDS with inhibitory effect on MRP2 including...