Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle

• Main Authors: Petter S. Alm (Author), Thais de Castro Barbosa (Author), Romain Barrès (Author), Anna Krook (Author), Juleen R. Zierath (Author)
• Format: Book
• Published: Elsevier, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Parental nutrition and lifestyle impact the metabolic phenotype of the offspring. We have reported that grandpaternal chronic high-fat diet (HFD) transgenerationally impairs glucose metabolism in subsequent generations. Here we determined whether grandpaternal diet transgenerationally imp...