Therapeutic effects of engineered exosome-based miR-25 and miR-181a treatment in spinocerebellar ataxia type 3 mice by silencing ATXN3

Abstract Background Spinocerebellar ataxia type 3 (SCA3) is the most common autosomal dominant hereditary ataxia worldwide, which is however in a lack of effective treatment. In view of that engineered exosomes are a promising non-invasive gene therapy transporter that can overcome the traditional p...

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Main Authors: Zhenchu Tang (Author), Shenglan Hu (Author), Ziwei Wu (Author), Miao He (Author)
Format: Book
Published: BMC, 2023-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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