Contributions of HFE polymorphisms to brain and blood iron load, and their links to cognitive and motor function in healthy adults

• Main Authors: Grégoria Kalpouzos (Author), Francesca Mangialasche (Author), Farshad Falahati (Author), Erika J Laukka (Author), Goran Papenberg (Author)
• Formato: Libro
• Publicado: Wiley, 2021-09-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Abstract Background Brain iron overload is linked to brain deterioration, and cognitive and motor impairment in neurodegenerative disorders and normal aging. Mutations in the HFE gene are associated with iron dyshomeostasis and are risk factors for peripheral iron overload. However, links to brain i...