Clinical covariates that improve the description of high dose methotrexate pharmacokinetics in a diverse population to inform MTXPK.org

• Main Authors: Zachary L. Taylor (Author), Tamara P. Miller (Author), Ethan A. Poweleit (Author), Nicholas P. DeGroote (Author), Lauren Pommert (Author), Oluwafunbi Awoniyi (Author), Sarah G. Board (Author), Ngozi Ugboh (Author), Vivek Joshi (Author), Nick Ambrosino (Author), Ashley Chavana (Author), Melanie B. Bernhardt (Author), Eric S. Schafer (Author), Maureen M. O'Brien (Author), Sharon M. Castellino (Author), Laura B. Ramsey (Author)
• Format: Book
• Published: Wiley, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The MTXPK.org webtool was launched in December 2019 and was developed to facilitate model‐informed supportive care and optimal use of glucarpidase following the administration of high‐dose methotrexate (HDMTX). One limitation identified during the original development of the MTXPK.org tool...