Saikosaponin D Inhibited IL-1β Induced ATDC 5 Chondrocytes Apoptosis In Vitro and Delayed Articular Cartilage Degeneration in OA Model Mice In Vivo

• Main Authors: Xinhui Wu (Author), Kangxian Zhao (Author), Xiaoxin Fang (Author), Feng Lu (Author), Pu Cheng (Author), Xiaoting Song (Author), Weikang Zhang (Author), Can Yao (Author), Jiling Zhu (Author), Haixiao Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoarthritis (OA) is the most common joint disease in the elderly, characterized by cartilage degradation and proliferation of subchondral bone. The pathogenesis of OA involves a variety of inflammatory mediators, including nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor (TNF)-α,...