Effects of pemphigus vulgaris serum on expression of Dsg and MMP-9 in HaCaT cells

• Main Authors: Zhi-min XIE (Author), Qiao-lin PAN (Author), Yi ZHANG (Author), Xu-cheng SHEN (Author), Hui-yan DENG (Author), Xiang-nong DAI (Author), Xing-dong YE (Author)
• Format: Book
• Published: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To investigate the effect of pemphigus vulgaris (PV) serum on expression of Desmoglein (Dsg)1, Dsg3 and matrix metalloproteinase 9 (MMP) 9 in HaCaT cells, and its pathogenic role in acantholysis. Method: This study included four experimental groups, i.e., normal control group, healthy-ser...