Drug resistance and treatment failure in leishmaniasis: A 21st century challenge.

• Main Authors: Alicia Ponte-Sucre (Author), Francisco Gamarro (Author), Jean-Claude Dujardin (Author), Michael P Barrett (Author), Rogelio López-Vélez (Author), Raquel García-Hernández (Author), Andrew W Pountain (Author), Roy Mwenechanya (Author), Barbara Papadopoulou (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reevaluation of treatment guidelines for Old and New World leishmaniasis is urgently needed on a global basis because treatment failure is an increasing problem. Drug resistance is a fundamental determinant of treatment failure, although other factors also contribute to this phenomenon, including th...