Novel therapeutic strategies targeting UCP2 in uterine leiomyosarcoma

• Main Authors: Yukari Nagao (Author), Akira Yokoi (Author), Kosuke Yoshida (Author), Mai Sugiyama (Author), Eri Watanabe (Author), Kae Nakamura (Author), Masami Kitagawa (Author), Eri Asano-Inami (Author), Yoshihiro Koya (Author), Masato Yoshihara (Author), Satoshi Tamauchi (Author), Yusuke Shimizu (Author), Yoshiki Ikeda (Author), Nobuhisa Yoshikawa (Author), Tomoyasu Kato (Author), Yusuke Yamamoto (Author), Hiroaki Kajiyama (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Uterine leiomyosarcoma (ULMS) is a malignant stromal tumor arising from the myometrium with a poor prognosis and very limited response to current chemotherapy. This study aimed to identify novel targets for ULMS through a three-step screening process using a chemical library consisting of 1271 Food...