A 3‐week nonalcoholic steatohepatitis mouse model shows elafibranor benefits on hepatic inflammation and cell death

• প্রধান লেখক: François Briand (লেখক), Christophe Heymes (লেখক), Lucile Bonada (লেখক), Thibault Angles (লেখক), Julie Charpentier (লেখক), Maxime Branchereau (লেখক), Emmanuel Brousseau (লেখক), Marjolaine Quinsat (লেখক), Nicolas Fazilleau (লেখক), Rémy Burcelin (লেখক), Thierry Sulpice (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2020-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The long duration of animal models represents a clear limitation to quickly evaluate the efficacy of drugs targeting nonalcoholic steatohepatitis (NASH). We, therefore, developed a rapid mouse model of liver inflammation (i.e., the mouse fed a high‐fat/high‐cholesterol diet, where cyclodextrin is co...