Polyphyllin I exerts anti-hepatocellular carcinoma activity by targeting ZBTB16 to activate the PPARγ/RXRα signaling pathway

• Main Authors: Lu shan (Author), Yijun Chen (Author), Guo An (Author), Xiaoyu Tao (Author), Chuanqi Qiao (Author), Meilin Chen (Author), Jiaqi Li (Author), Ruichao Lin (Author), Jiarui Wu (Author), Chongjun Zhao (Author)
• Format: Book
• Published: BMC, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Studies have reported that polyphyllin I (PPI) had effective anti-tumor activity against hepatocellular carcinoma (HCC). However, the precise molecular mechanism of this action and the direct target remain unclear. The aim of this study was to discover the molecular targets and t...