High Cefuroxime Concentrations and Long Elimination in an Orthopaedic Surgical Deadspace-A Microdialysis Porcine Study

• Main Authors: Sara Kousgaard Tøstesen (Author), Maiken Stilling (Author), Pelle Hanberg (Author), Theis Muncholm Thillemann (Author), Thomas Falstie-Jensen (Author), Mikkel Tøttrup (Author), Martin Knudsen (Author), Emil Toft Petersen (Author), Mats Bue (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Deadspace is the tissue and bony defect in a surgical wound after closure. This space is presumably poorly perfused favouring bacterial proliferation and biofilm formation. In arthroplasty surgery, an obligate deadspace surrounding the prosthesis is introduced and deadspace management, in combinatio...