Effect of N-acetylcysteine on craving in substance use disorders (SUD): a meta-analysis of randomized controlled trials

• Main Authors: Micol Cuocina (Author), Giuseppe Aiello (Author), Pierfelice Cutrufelli (Author), Martina Rampello (Author), Laura Rapisarda (Author), Alessandro Rodolico (Author), Giuseppina Cantarella (Author), Maria Salvina Signorelli (Author), Renato Bernardini (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundN-acetyl cysteine (NAC) appears promising as a treatment in patients with substance use disorder (SUD) as it helps rebalance glutamate levels in the central nervous system (CNS). Basal concentrations of glutamate are indeed reduced in SUD patients but increased during craving.Materials and...