Risk-Assessment Implications of Mechanistic Model's Prediction of Low-Dose Nonlinearity of Liver Tumor Risk for Mice FED Fumonisin B
A two-stage, clonal-expansion model of liver tumor risk in mice was developed by Kodell et al. (Food Addit Contam 18:237-253, 2001) based on the hypothesis that fumonisin B 1 , a naturally occurring mycotoxin in corn, is not genotoxic, but rather causes cancer through the disruption of sphingolipid...
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SAGE Publishing,
2004-01-01T00:00:00Z.
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