Exposure of Infants to Isoniazid via Breast Milk After Maternal Drug Intake of Recommended Doses Is Clinically Insignificant Irrespective of Metaboliser Status. A Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach to Estimate Drug Exposure of Infants via Breast-Feeding

Isoniazid is a first-line anti-tuberculosis drug recommended for treatment of drug-susceptible Mycobacterium tuberculosis infections. Breast-feeding is not contra-indicated while undergoing isoniazid therapy, even though isoniazid was found to migrate into breast milk, leading to infant drug exposur...

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Main Authors: Estella Dora Germaine Garessus (Author), Hans Mielke (Author), Ursula Gundert-Remy (Author)
Format: Book
Published: Frontiers Media S.A., 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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