17beta-estradiol and testosterone influence the mRNA expression and the time course of inflammatory cytokines in activated human monocytic cell line (THP-1)

• Main Authors: C. Craviotto (Author), A. Sulli (Author), P. Montagna (Author), B. Villaggio (Author), S. Capellino (Author), M. Cutolo (Author)
• Format: Book
• Published: PAGEPress Publications, 2011-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The aim of this study was to evaluate the effects of 17b-estradiol (E2) and testosterone (T) on the mRNA expression of IL-1b, IL-6, TNF-a and TGF-b in cultured human monocytic cells (THP-1) after INF-g activation. Methods: THP-1 were cultured with E2 and T (10 nM) for 24 hs and then activ...