Design, Synthesis, In Vitro Biological Activity Evaluation and Stabilized Nanostructured Lipid Carrier Formulation of Newly Synthesized Schiff Bases-Based TMP Moieties

• Main Authors: Syed Nasir Abbas Bukhari (Author), Mohamed Y. Zakaria (Author), Muhammad Usman Munir (Author), Naveed Ahmad (Author), Mervat A Elsherif (Author), Rasha Emad Badr (Author), Ahmad Khalaf Hassan (Author), Ali H. Abu Almaaty (Author), Islam Zaki (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of novel Schiff bases-based TMP moieties have been designed and synthesized as potential anticancer agents. The target Schiff bases were screened for their cytotoxic activity against the MDA-MB-231 breast cancer cell line. Most of the tested molecules revealed good cytotoxic activity, espec...