SiON_x Coating Regulates Mesenchymal Stem Cell Antioxidant Capacity via Nuclear Erythroid Factor 2 Activity under Toxic Oxidative Stress Conditions

• Main Authors: Neelam Ahuja (Author), Kamal Awad (Author), Su Yang (Author), He Dong (Author), Antonios Mikos (Author), Pranesh Aswath (Author), Simon Young (Author), Marco Brotto (Author), Venu Varanasi (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Healing in compromised and complicated bone defects is often prolonged and delayed due to the lack of bioactivity of the fixation device, secondary infections, and associated oxidative stress. Here, we propose amorphous silicon oxynitride (SiON_x) as a coating for the fixation...