Association of <i>F. alocis</i> and <i>D. pneumosintes</i> with Periodontitis Disease Severity and Red Complex Bacteria

• Main Authors: Hawaabi F. M. Shaikh (Author), Pratima U. Oswal (Author), Manohar Suresh Kugaji (Author), Sandeep S. Katti (Author), Kishore Gajanan Bhat (Author), Eswar Kandaswamy (Author), Vinayak M. Joshi (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Oral biofilms are considered the principal etiological agent in the development of periodontitis. Novel species that may contribute to periodontitis and dysbiosis have been identified recently. The study aims to evaluate the presence of <i>F. alocis</i> and <i>D. pneumosintes</i> in healthy and diseased patients and their association with clinical parameters and with red complex bacteria. The study included 60 subjects, with 30 patients each in the healthy and periodontitis groups. The clinical parameters were noted, and samples were subjected to DNA extraction followed by a polymerase chain reaction. Statistical analysis was performed using the Graph Pad Prism software. Results: <i>F. alocis</i> and <i>D. pneumosintes</i> were detected at a significantly higher percentage in the periodontitis group compared to the healthy group (<i>p</i> < 0.05). <i>D. pneumosintes</i> was significantly associated with <i>T. forsythia</i> in the periodontitis group (<i>p</i> < 0.05). Both of these organisms were present in sites with higher clinical attachment loss (<i>p</i> < 0.05). This study demonstrated that both <i>F. alocis</i> and <i>D. pneumosintes</i> were detected at a significantly higher percentage in periodontitis subjects and were detected more frequently in sites with a greater clinical attachment loss. It was also evident that both <i>F. alocis</i> and <i>D. pneumosintes</i> can be present independently of other putative periodontal pathogens.

Item Description

10.3390/dj12040105
2304-6767