Synthesis and preliminary structure-activity relationship study of 2-aryl-2H-pyrazolo[4,3-c]quinolin-3-ones as potential checkpoint kinase 1 (Chk1) inhibitors

The serine-threonine checkpoint kinase 1 (Chk1) plays a critical role in the cell cycle arrest in response to DNA damage. In the last decade, Chk1 inhibitors have emerged as a novel therapeutic strategy to potentiate the anti-tumour efficacy of cytotoxic chemotherapeutic agents. In the search for ne...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Ivana Malvacio (Auteur), Alberto Cuzzolin (Auteur), Mattia Sturlese (Auteur), D. Mariano A. Vera (Auteur), E. Laura Moyano (Auteur), Stefano Moro (Auteur)
Formaat: Boek
Gepubliceerd in: Taylor & Francis Group, 2018-01-01T00:00:00Z.
Onderwerpen:
Online toegang:Connect to this object online.
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Internet

Connect to this object online.

3rd Floor Main Library

Exemplaargegevens van 3rd Floor Main Library
Plaatsingsnummer: A1234.567
Kopie 1 Beschikbaar