S100A8/A9 as a risk factor for breast cancer negatively regulated by DACH1

• Main Authors: Xiaojun Zhang (Author), Mengke Niu (Author), Tianye Li (Author), Yuze Wu (Author), Jinnan Gao (Author), Ming Yi (Author), Kongming Wu (Author)
• Format: Book
• Published: BMC, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background S100A8 and S100A9 are members of Ca2+-binding EF-hand superfamily, mainly expressed by macrophages and neutrophils. Limited by the poor stability of homodimers, they commonly exist as heterodimers. Beyond acting as antibacterial cytokines, S100A8/A9 is also associated with metabo...