Accelerated tooth movement in Rsk2-deficient mice with impaired cementum formation

• Main Authors: Cita Nottmeier (Author), Maximilian G. Decker (Author), Julia Luther (Author), Simon von Kroge (Author), Bärbel Kahl-Nieke (Author), Michael Amling (Author), Thorsten Schinke (Author), Julian Petersen (Author), Till Koehne (Author)
• Format: Book
• Published: Nature Publishing Group, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Coffin-Lowry-Syndrome (CLS) is a X-linked mental retardation characterized by skeletal dysplasia and premature tooth loss. We and others have previously demonstrated that the ribosomal S6 kinase RSK2, mutated in CLS, is essential for bone and cementum formation; however, it remains to be es...