High rate of mutations in the BRCA1, BRCA2, CHEK2, NBN, and BLM genes in Russian ovarian cancer patients

• Autori principali: Ye. I. Bateneva (Autore), M. G. Filippova (Autore), A. S. Tyulyandina (Autore), A. A. Meshcheryakov (Autore), K. I. Zhordania (Autore), A. N. Gritsai (Autore), V. V. Kadochnikova (Autore), D. D. Abramov (Autore), A. A. Ragimov (Autore), D. Yu. Trofimov (Autore), L. N. Lyubchenko (Autore)
• Natura: Libro
• Pubblicazione: ABV-press, 2015-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Background. The early diagnosis of ovarian cancer (OC) is an important problem in modern gynecological oncology due to significant detection rates for late-stage tumors. Intensive screening of patients from high-risk groups that include OC predisposition gene mutation carriers is indicated.Subjects...