Sanse Powder Essential Oil Nanoemulsion Negatively Regulates TRPA1 by AMPK/mTOR Signaling in Synovitis: Knee Osteoarthritis Rat Model and Fibroblast-Like Synoviocyte Isolates

• Hauptverfasser: Mingchao Li (VerfasserIn), Li Zhang (VerfasserIn), Zixiu Liu (VerfasserIn), Runlin Xing (VerfasserIn), Songjiang Yin (VerfasserIn), Xiaochen Li (VerfasserIn), Nongshan Zhang (VerfasserIn), Peimin Wang (VerfasserIn)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2021-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Synovitis is the primary driving factor for the occurrence and development of knee osteoarthritis (KOA) and fibroblast-like synoviocytes (FLSs) and plays a crucial role during this process. Our previous works revealed that transient receptor potential ankyrin 1 (TRPA1) ion channels mediate the ampli...