Successful application of the strategy of blastocyst biopsy, vitrification, whole genome amplification, and thawed embryo transfer for preimplantation genetic diagnosis of neurofibromatosis type 1

• Main Authors: Yi-Lin Chen (Author), Chia-Cheng Hung (Author), Shin-Yu Lin (Author), Mei-Ya Fang (Author), Yi-Yi Tsai (Author), Li-Jung Chang (Author), Chien-Nan Lee (Author), Yi-Ning Su (Author), Shee-Uan Chen (Author), Yu-Shih Yang (Author)
• Format: Book
• Published: Elsevier, 2011-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Preimplantation genetic diagnosis (PGD) offers an alternative for women to carry an unaffected fetus risk of hereditary diseases. Trophectoderm biopsy may provide more cells for accurate diagnosis. However, the time allowed for transportation of the specimens to the laboratory and perform...