A "genome-to-lead" approach for insecticide discovery: pharmacological characterization and screening of Aedes aegypti D(1)-like dopamine receptors.

• Main Authors: Jason M Meyer (Author), Karin F K Ejendal (Author), Larisa V Avramova (Author), Elisabeth E Garland-Kuntz (Author), Gloria I Giraldo-Calderón (Author), Tarsis F Brust (Author), Val J Watts (Author), Catherine A Hill (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Many neglected tropical infectious diseases affecting humans are transmitted by arthropods such as mosquitoes and ticks. New mode-of-action chemistries are urgently sought to enhance vector management practices in countries where arthropod-borne diseases are endemic, especially where vec...