Case Report: Safety and Efficacy of Denosumab in Four Children With Noonan Syndrome With Multiple Giant Cell Lesions of the Jaw

Noonan syndrome is a genetic disorder caused by mutations in the RAS/MAPK pathway. Multiple giant cell lesions are a rare sequelae of disruptions in this pathway, termed Noonan-like multiple giant cell lesions (NL/MGCLs). Medical management of these tumors rather than surgical intervention is prefer...

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Main Authors: Kristen Ferriero (Author), Biraj Shah (Author), Yun Yan (Author), Surya Khatri (Author), John Caccamese (Author), Joseph A. Napoli (Author), Michael B. Bober (Author), Janet L. Crane (Author)
Format: Book
Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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